Due to the findings of this study the surgeons have begun AF-treatment of more patients undergoing GI-surgery in which through experience the outcome is known to lead to reduced intestinal function.
The treatment is initiated by already on the first day administer Salovum® dissolved in ordinary juice. This will quickly lead to high AF levels in the intestine without first letting the body produce it by its own. Most often the patients initially treated with Salovum® for 5-10 days can then be transferred to the AF inducing SPC-Flakes® in order to stimulate the endogenous AF production.
Björck, Bosaeus, Ek, Jennische, Lönnroth, Johansson and Lange, Food induced stimulation of the antisecretory factor can improve symptoms in human inflammatory bowel disease: A study of a concept, Gut, 2000; 46:824-829, view link
SPC-Flakes® in the treatment of severe Crohn's disease
Prior positive results from AF-treatment on Crohn's patients encouraged an open study on a group of six patients with severe, prolonged treatment resistant Crohn's disease. Patients were treated with AF inducing cereals during three months. Clinical symptoms, blood samples, endoscopic and histological examination, CDAI (Crohn's Disease Activity Index) and quality of life (SF-36) were evaluated.
A continuous and significant improvement of clinical symptoms and quality of life measurements was seen as well as histological improvement. Findings from this and earlier studies show the anti-inflammatory activity of the specially processed AF inducing cereals. It is most likely that it is the anti-inflammatory activity that is of greatest importance in the treatment of Crohn's patients.
Shafazand, Eriksson, Jennische och Lange, Födoinducerad ökning av antisekretorisk faktor förbättrade det kliniska tillståndet hos sex patienter med svår Crohns sjukdom, Posterpresentation vid Riksstämman, 2003
SPC-Flakes® in IBD in children
The first pilot study in children with ulcerative colitis and Crohn's disease revealed that the clinical symptoms improved and that treatment with SPC-Flakes is a safe and well tolerated treatment. The positive study results will be followed up with a randomised double-blind study.
Finkel, Bjarnason, Lindblad and Lange, Specially Processed Cereals: A clinical innovation for children suffering from inflammatory bowel disease?, Scand J of Gastroenterol, 2004; 39:87-88, view link