There have been several studies since the late 1980s with the SPC-feed given to pigs. Most of these studies are made in Sweden and they have clearly demonstrated that this feed both reduces the incidence of diarrhoea and increases pig growth.
Since there is a large international interest in finding alternatives to animal feed with antibiotics, there are studies ongoing abroad. An Italian research team has recently highlighted a study that also shows that AF-inducing cereals have both antisecretory and anti-inflammatory properties.
Please find below some study references:
McEwan, Schousboe and Skadhauge, Effect of antisecretory factor on Escherichia coli Sta enterotoxin-induced alkalinisation of pig jejunal acid microclimate , Pflügers Arch , 1990; 417:174-179 see link
McEwan, Schousboe and Skadhauge, Influence of Age on Antisecretory Factor Inhibition of Enterotoxin Action in the Pig Small Intestine, J Vet Med A 38, 1991:222-228 see link.
Göransson, Martinsson, Lange and Lönnroth, Feed-induced Lectins in Piglets, J Vet Med B 40, 1993:478-484see link
Göransson, Lange and Lönnroth, Post weaning diarrhea: focus on diet, Pig News and Information, Vol 16, No 3,1995:89N-91N
Bolduan, Schuldt and Hackl, Diet feeding in weaner piglets, Arch Tierz, Dummerstorf 40, Sonderheft, 1997:95-100
Garnsworthy and Wiseman, Alternatives to Antibiotics – The Influence of New Feeding Strategies for Pigs on Biology and Performance, Recent Developments in Pig Nutrition 3, Nottingham University Press, 2001
Ulgheri, Grilli, Rossi and Piva, Effect of hydrothermally processed cereals on performance of weaned piglets, Livestock Science, Vol 134, Issue 1, 2010:166-168 see link